Jon Lowrance 

• Cell Biology
• Virology
• Immunology
• Apoptosis

Jon mentors several students each year in research projects focusing on the human innate immune responses to short chain fatty acids and Toll-Like Receptor 4 expression in different eukaryotic cell types. These students have presented their data at local, state and regional meetings, including the regional meeting of American Society of Microbiology.

Gresham, H. D., Lowrance, J. H., Caver, T. E., Wilson, B. S., & Linberg, F. P. (2000).  Survival of Staphylococcus aureus Inside Neutrophils Contributes to Infection.   Journal of Immunology, 200, 3713-3722. 

Lowrance, J. H., O'Sullivan, F., Caver, T. E., Waegell, W., & Gresham, H. D. (1994).  

Spontaneous Elaboration of TGF-ß Suppresses Host Defense against Bacterial Infection in Autoimmune MRL/lpr Mice.   J. Experimental Med., 180, 1693-1703. 

Baddour, L. M., Lowrance, C., Lowrance, J. H., Albus, A., & Lee, J. C. (1992).  Staphylococcus aureus Microcapsule Expression Attenuates Bacterial Virulence in a Rat Model of Experimental Endocarditis.   J. Infect. Dis., 165, 749-753. 

Lowrance, J. H., Baddour, L. M., & Simpson, W. A. (1990).  The Role of Fibronectin in Streptococcus sanguis Infective Endocarditis.   Journal of Clinical Investigation, 86, 7.13. 

Christensen, G. D., Baddour, L. M., Madison, B. M., Simpson, W. A., & Lowrance, J. H. (1990).  Colonial Morphology of Staphylococci on Memphis Agar: Phase Variation of Slime Production, Resistance to Beta-Lactam Antibiotics, and Virulence.   J. Infect. Dis., 161, 1153-1169. 

Weems, J. J., Lowrance, J. H., Simpson, W. A., & Baddour, L. M. (1989).  Molecular epidemiology of nosocomial, multiple aminoglycosides resistant Enterococcus faecalis.   J. Antimicrobial Chemotherapy, 24, 121-130. 

Baddour, L. M., Christensen, G. D., Lowrance, J. H., & Simpson, W. A. (1989).  Pathogenesis of Experimental Endocarditis.   Reviews of Infect. Dis, 11, 452-463. 

Lowrance, J. H., Hasty, D. L., & Simpson, W. A. (in press, 1988).  Adherence of Streptococcus sanguis to conformationally specific determinants on fibronectin.   Infection and Immunity.

• 2018-2019: Outstanding Teacher, Lipscomb University. Outstanding Reacher Award 2019
• 2006-2007: John William Baker Summer Fellowship Award
• 2006-2007: Outstanding Teacher, Lipscomb University. Outstanding Teacher Award for 2006
• 1997-1998: Outstanding Teacher, Lipscomb University. Outstanding Teacher Award for 1997

Local 

Cunningham, S. & Lowrance, J. H. (2018-2019). NOD2 Mutations in Crohn's disease.  Lipscomb University Biomedical Research Symposium, Nashville, Tennessee. 

Edmonds, S. & Lowrancer, J. H. (2018-2019). Expression of TLR4 in Cancerous and Non-cancerous Colorectal Epithelial Cell Lines in Response to Short Chain Fatty Acids. Invited presentation at Lipscomb University Student Scholars Symposium, Nashville, Tennessee. 

Hibma, J. L. & Lowrance, J. H. (2018-2019). Short Chain Fatty Acid Regulation of Toll-Like Receptor 4 in Colorectal Epithelial Cells. Invited presentation at Lipscomb University Student Scholars Symposium, Nashville, Tennessee. 

McCormack, K. A. & Lowrance, J. H. (2018-2019). Presence of TLR4 in Primary Gingival Cells from Buccal Washes.  Lipscomb University Biomedical Research Symposium, Nashville, Tennessee. 

Seal, J. T. & Lowrance, J. H. (2018-2019). Trisomy 21 as a Mechanism to Increase the Likelihood of Leukemia in Early Childhood.  Lipscomb University Biomedical Research Symposium, Nashville, Tennessee. 

Watson, M. & Lowrance, J. H. (2018-2019). Molecular Profiling of Ehrlichia chaffeensis and Borrelia burgdorferi in Davidson and Wilson County, Tenessee.  Lipscomb University Biomedical Research Symposium, Nashville, Tennessee. 

Lowrance, J. H., Ankenbauer, K. E., & Kemper, K. J. (2017-2018). The Localization of the TLR 4/MD2 Complex in Colonic Epithelial Cells after Stimulation with SCFAs. Invited presentation at Lipscomb University Student Scholars Symposium, Nashville, Tennessee. 

Lowrance, J. H. & Vasseur, C. (2017-2018). TLR 4 Associated GPR41 Expression Due to SCFA Stimulation. Invited presentation at Lipscomb University Student Scholar Symposium, Nashville, Tennessee. 

Mahon, C. (2017-2018, April). Toll-Like Receptor Roles in Periodontal Diseases.  Lipscomb University Biomedical Research Symposium, Nashville, United States of America. 

McNaught, J. (2017-2018, April). Neuronal Degradation a Hallmark of Huntington's Disease.  Lipscomb University Biomedical Research Symposium, Nashville, United States of America. 

Byrd, J. & Lowrance, J. H. (2015-2016, April). BDNF Signal Starvation via TrkB Inhibition in MDA-MB-231 Breast Adenocarcinoma Cells.  Lipscomb University Student Scholars Symposium, Nashville, Tennessee. 

Couch, C. & Lowrance, J. H. (2015-2016, April). Short Chain Fatty Acid Stimulation of TLR-4 in Intestinal Epithelial Cells.  Lipscomb University Biomedical Research Symposium, Nashville, Tennessee. 

Hancock, T. & Lowrance, J. H. (2015-2016, April). Comparing Apoptotic Marker Expression Among Breast Cell Lines.  Lipscomb University Biomedical Research Symposium, Nashville, Tennessee. 

Schultz, J. & Lowrance, J. H. (2015-2016, April). Dengue Virus Pathogenesis: Genetic Targeting Using RIG-1-like Receptors and IRF-3/7.  Lipscomb University Student Scholars Symposium, Nashville, Tennessee. 

Hampton, G. & Lowrance, J. H. (2015-2016, December). Comparison of Apoptotic Component Expression Between Normal Cells and Breast Cancer Cells, MDA-MB-231 AND MCF-7.  Lipscomb University Biomedical Research Symposium, Nashville, Tennessee.

 Klein, A. & Lowrance, J. H. (2014-2015, April). Expression of Toll-Like Receptors in NCM Normal Colon Cell and HT-29 P53 Colon Cancer Cells.  Lipscomb University Biomedical Research Symposium, Nashville, Tennessee. 

Shin, J. & Lowrance, J. H. (2014-2015, April). Human Brain Derived Neurotrophic Factor Exon Profile in Breast Cancer Cells MDA-MB-231 and MCF-7.  Lipscomb University Biomedical Research Symposium, Nashville, Tennessee. 

Regional 

Owens, J. A. & Lowrance, J. H. (2015-2016, September). Short chain fatty acids stimulation of TLR4 expression in intestinal epithelial cells.  American Society of Microbiology-Kentucky/Tennessee Branch, Murfreesboro, Tennessee. 

State 

Lowrance, J. H. & McNeil, J. B. (2013-2014). Exon Profile of Human Brain Derived Neurotrophic Factor (BDNF) in Non-Cancerous Breast Epithelium Using HMEC and MCF-10A Cells Lines.  Tennessee Academy of Science, Tullahoma, Tennessee. 

Hall, A., Burch, A., & Lowrance, J. H. (2010-2011). Brain-Derived Neurotrophic Factor (BDNF) Expression in MDA-MB-231 Cancer Cells.  Tennessee Academy of Science, Nashville, Tennessee. 

Maerz, P., Brawner, K., & Lowrance, K. H. (2010-2011). BDNF Expression in a Prostate Cancer Cell Line.  Tennessee Academy of Science, Nashville, Tennessee. 

Pannell, J., Burch, A., Lowrance, J. H., & Gallaher, K. (2010-2011). Effects of Bio-One on the Nitrogen Fixation Process.  Tennessee Academy of Science, Nashville, Tennessee. 

Downs, R. & Lowrance, J. H. (1998-1999). PCR Analysis of Phase Variation of Type1 Fimbriae in Escherichia coli.  Tennessee Academy of Science, Clarksville, Tennessee. 

Finch, L., Luther, M., Holliday, S., Lowrance, J. H., & Clinger, K. (1996-1997). Growth Conditions Allowing for Expression of Tyrosine Decarboxylase in Chromobacterium violaceum.  Tennessee Academy of Science, Sewanee, Tennessee. 

Holliday, S., Clinger, K., & Lowrance, J. H. (1996-1997). Detection of Tyrosine Decarboxylase Activity in Chromobacterium violaceum.  Tennessee Academy of Science, Clarksville, Tennessee. 

• Nashville Habitat for Humanity
• Brentwood Hills Church of Christ